AML Research

Many individuals with acute myeloid leukemia (AML) are excluded from new drug studies for varied reasons like a bad performance evaluation, abnormal kidney, liver or heart function, disease with hepatitis or individual immune deficiency-related viruses, evaluations conducted outside narrow-specified time periods, co-morbidities, frailty, or even a previous cancer when danger of recurrence is very low These conditions radically limit clinical trials eligibility, particularly in elderly individuals.

Research into exceptions in oncology clinical trials has concentrated nearly exclusively on persons using solid neoplasms.

Though our very first problem calls for systemic, unquantified choice biases, the next, ironically, is unrestricted use of medication post acceptance.

A subtler but more prevalent bias works when otherwise-eligible persons aren’t even considered for a clinical trial, frequently due to the understanding that they are a bad study candidate. Regrettably, most studies don’t report the amount of men screened, registered, or excluded as a percentage of qualified persons; also this doesn’t include the substantial numbers of topics never screened or referred to a research website.